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Nutrition & Formula

Inside Stress + Gut: The Thinking Behind the Formula

Everyday stress and gut comfort belong in the same conversation. Discover why Resilio brings probiotics, L-theanine, ashwagandha and vitamin B6 into one daily formula.

Resilio Stress + Gut bottle and two capsules on a blue studio surface

The short read

Stress + Gut is a multi-ingredient stress and gut–brain nutrition formula, designed for everyday calm and gut comfort.* It brings three named probiotic strains, L-theanine, ashwagandha root extract and vitamin B6 into one two-capsule serving.

The meeting ends, and your mind keeps going. Lunch is over, and your stomach still feels unsettled. On a demanding day, feeling mentally at ease and comfortable in your gut can matter at the same time.

That connection shaped Stress + Gut. We brought ingredients with different nutritional roles into one formula, so support for these connected needs has a simple place in your day.

Why these ingredients belong together.

The design starts with an everyday goal: a calmer mind and a more comfortable gut.* To build around that goal, we chose ingredients for three roles:

  • The gut–brain dimension. CEREBIOME® R0052 + R0175 brings a pair studied together for psychological wellbeing. Alongside R0011, it forms the three-strain probiotic part of the formula.
  • Everyday stress support. L-theanine and ashwagandha bring an amino acid and a botanical into the design, drawing on human research into stress-related wellbeing and rest.
  • Essential nervous system nutrition. Vitamin B6 contributes to normal nervous system function, including the production of neurotransmitters.

These roles explain the combination: a gut–brain focus, ingredients selected for everyday stress support, and a nutrient involved in the body's daily signalling processes. Bringing them into one serving also makes the routine practical, with the formula already assembled for you.

Inside your two-capsule serving.

Each bottle contains 30 capsules, providing 15 servings. Here is the complete active-ingredient breakdown.

Per two-capsule serving
Ingredient Amount
CEREBIOME®: Lactobacillus helveticus R0052 + Bifidobacterium longum subsp. longum R0175 3 billion CFU
Lacticaseibacillus rhamnosus R0011 1 billion CFU
L-theanine 200 mg
Ashwagandha root extract 300 mg
Vitamin B6, from pyridoxal-5-phosphate monohydrate 3 mg · 176% DV

The probiotic blend provides 4 billion CFU at manufacture and weighs 37.42 mg. CFU means colony-forming units. DV means Daily Value.

The gut–brain dimension: three named strains.

We selected the probiotic component around the formula’s gut–brain focus. Naming each strain connects the choice to the particular microorganisms used in the research.

CEREBIOME®: the gut–brain focus

CEREBIOME® combines L. helveticus R0052 and B. longum R0175. Stress + Gut provides 3 billion CFU of this pair per serving.

The pair has been studied together in human research on psychological wellbeing. In a randomized, placebo-controlled study, healthy volunteers took the combination for 30 days, and researchers reported improvements in psychological-distress measures. [1]

That research is a reason for choosing this pair: it connects a probiotic ingredient to the everyday experience of mental wellbeing, giving the gut–brain dimension a specific place in the design.

R0011: completing the three-strain blend

Lacticaseibacillus rhamnosus R0011 contributes a further 1 billion CFU per serving. Together with R0052 and R0175, it completes the three-strain blend, which provides a total of 4 billion CFU at manufacture.

L-theanine: a researched approach to calm.

A busy day can leave little space to settle. L-theanine is the amino acid we chose for the calm-focused side of Stress + Gut, with 200 mg in each two-capsule serving.

That daily amount has been used in human research. A 2019 randomized, double-blind crossover trial in 30 adults studied 200 mg daily during four-week intervention periods. Researchers reported improvements in sleep-latency and sleep-disturbance questionnaire scores compared with placebo. [2]

At 200 mg per serving, L-theanine brings an amount used in published human research into the formula’s approach to everyday calm and the transition from a demanding day to rest.

Ashwagandha: the botanical choice for everyday stress.

Stress + Gut includes 300 mg of ashwagandha root extract per serving. Ashwagandha has a long history of use in Ayurvedic traditions and is the subject of modern human research on stress and sleep. [3]

We chose ashwagandha to give the formula a botanical approach to stress-related support. Its traditional use and modern research fit the same everyday priority behind our choice of L-theanine: making room for calm amid the demands of real life.

Vitamin B6: nutrition for the nervous system.

Vitamin B6 helps the body make neurotransmitters, the chemical messengers used by the nervous system. It also participates in more than 100 enzyme reactions. These everyday functions give B6 its role in the formula. [4]

Stress + Gut provides 3 mg of vitamin B6 from pyridoxal-5-phosphate monohydrate, supplying 176% of the Daily Value per serving. Alongside the probiotic, amino-acid and botanical components, B6 supplies an essential nutrient for normal nervous system function.

Designed around the way the day feels.

Feeling composed through a full afternoon. Feeling comfortable in your gut. Having a daily routine that is easy to return to. These are the priorities behind Stress + Gut.

Our formula brings stress and gut–brain nutrition into the same daily moment. Each ingredient has a role, and two capsules bring those choices together in a format that fits around work, travel and life at home.

One daily serving. A shared purpose: everyday calm and gut comfort.*

Resilio Stress + Gut. Stress & Gut-Brain Nutrition for Real Life.

Explore Stress + Gut for the complete formula, directions and current availability.

Explore Stress + Gut

For the everyday science behind this connection, read Why Stress Can Change How Your Gut Feels.

Ingredient research

The references below describe research on the individual ingredients and preparations studied.

  1. Messaoudi et al. (2011). R0052 + R0175 and psychological wellbeing. British Journal of Nutrition.
  2. Hidese et al. (2019). L-theanine, stress-related symptoms and cognitive functions. Nutrients.
  3. NCCIH. Ashwagandha: Usefulness and Safety.
  4. NIH Office of Dietary Supplements. Vitamin B6: Health Professional Fact Sheet.
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Find your daily support.

R1 / Ingredient guide

R1 / Five active ingredients

All five active ingredients.

Explore their roles and why we chose them. Amounts shown are per 1 sachet (9 g) of R1 White Yuzu.

SIGNAL

CP2305

10 billion cell equivalent per sachet

A heat-treated strain of L. gasseri, selected for its human research on stress and sleep. A defined role in R1's gut–brain approach.

RESERVE

Creatine Monohydrate

3,000 mg per sachet

Supports the phosphocreatine system, which helps store and supply energy in cells.

STATE

L-Theanine

200 mg per sachet

An amino acid naturally found in tea, selected for human research on stress-related measures and attention. Its role in R1 is support for a calmer state.

RECOVERY SUPPORT

L-Ornithine HCl

500 mg per sachet

An amino acid selected for research on stress, fatigue and perceived sleep quality. One supporting role within the wider formula.

GUT SUPPORT

PHGG

3,000 mg per sachet

Partially hydrolyzed guar gum, a soluble prebiotic fiber selected to support the gut environment.
Resilio / Explore

R1 / SIGNAL

CP2305

A heat-treated strain of L. gasseri, selected for its human research on stress and sleep. A defined role in R1's gut–brain approach.

What was studied

Randomized, double-blind, placebo-controlled trial

In a 24-week trial, heat-inactivated CP2305 improved anxiety and sleep-disturbance scores compared with placebo in Japanese medical students preparing for examinations.

Study context: 60 students; the heat-inactivated CP2305 preparation; an examination-stress setting.

Nishida et al. · Nutrients · 2019 (opens in a new tab)

Five active ingredients. One daily recovery routine.

Resilio / Explore

R1 / RESERVE

Creatine Monohydrate

Supports the phosphocreatine system, which helps store and supply energy in cells.

What was studied

Human muscle-creatine study

The study compared creatine intake protocols in men. A 3 g daily protocol increased muscle creatine gradually over 28 days, without a high-dose loading phase.

Measured outcome: muscle creatine concentration in men, including a 3 g daily protocol over 28 days.

Hultman et al. · Journal of Applied Physiology · 1996 (opens in a new tab)

Five active ingredients. One daily recovery routine.

Resilio / Explore

R1 / STATE

L-Theanine

An amino acid naturally found in tea, selected for human research on stress-related measures and attention. Its role in R1 is support for a calmer state.

What was studied

Randomized, placebo-controlled crossover trial

L-theanine at 200 mg daily improved sleep-latency and sleep-disturbance scores compared with placebo in a four-week intervention.

Ingredient study: 30 adults; 200 mg L-theanine daily; four weeks per intervention.

Hidese et al. · Nutrients · 2019 (opens in a new tab)

Five active ingredients. One daily recovery routine.

Resilio / Explore

R1 / RECOVERY SUPPORT

L-Ornithine HCl

An amino acid selected for research on stress, fatigue and perceived sleep quality. One supporting role within the wider formula.

What was studied

Randomized, double-blind, placebo-controlled trial

52 Japanese adults with mild stress and fatigue were assigned L-ornithine or placebo for eight weeks. The study assessed stress markers, mood and perceived sleep quality.

Ingredient study: 52 adults; eight weeks; 500 mg L-ornithine monohydrochloride daily, supplying 400 mg L-ornithine.

Miyake et al. · Nutrition Journal · 2014 (opens in a new tab)

Five active ingredients. One daily recovery routine.

Resilio / Explore

R1 / GUT SUPPORT

PHGG

Partially hydrolyzed guar gum, a soluble prebiotic fiber selected to support the gut environment.

What was studied

Randomized, double-blind, placebo-controlled trial

Adults took 3 g or 5 g of PHGG dietary fiber daily for eight weeks. Researchers examined bowel measures, gut microbiota and quality-of-life questionnaires.

Ingredient study: 3 g and 5 g PHGG daily for eight weeks. Changes in selected gut bacteria were observed in both groups; bowel, sleep and motivation questionnaire improvements were significant in the 5 g group.

Abe et al. · Journal of Clinical Biochemistry and Nutrition · 2023 (opens in a new tab)

Five active ingredients. One daily recovery routine.

Resilio / Explore

Resilio / Find your fit

Recovery has to fit real life.

Start with the role you want nutritional support to play: an everyday foundation or a more targeted focus.

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Meet R1: five active ingredients in a daily powder, designed for recovery support. 30 sticks · 30 daily servings.

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For a more specific focus

Stress + Gut combines CEREBIOME® probiotics, R0011, L-theanine, ashwagandha and vitamin B6 for everyday stress and gut support.

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Compare the focus, ingredients and daily format of each product.

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Targeted recovery support

Stress + Gut

R1 is the daily recovery foundation in the Resilio range. Stress + Gut brings a targeted focus to everyday stress and gut support, in two daily capsules.

Different roles. One approach.

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